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Our Research

Here you'll find information about our Flagship programs and other projects. Use the filters below to display research of interest using one of the three categories.
  • T2,T3 | Flagship 2 Pilot and Seed
    Jessica Lee & team: Multidisciplinary Management Of Episodic Breathlessness In Adults With Advanced Cancer - a mixed methods pilot study of a complex intervention
    This T2 project involves development and evaluation of a complex intervention to improve episodic breathlessness in adults with advanced cancer. This intervention will comprise a patient held epis...
    Clinical Trials
  • T1 | Flagship 2 Pilot and Seed
    Helen McGuire: Development of a novel test to predict clinical response to checkpoint therapy in lung cancer and mesothelioma
    Immune checkpoint inhibitor therapy has provided new hope to cancer patients whose tumours have resisted conventional therapy. One of the most recent success stories has been effective treatment o...
    ImmunotherapyNew therapies and diagnosticsLung cancerMesothelioma
  • T1 | Flagship 2 Pilot and Seed
    Thomas Cox: Biomechanical priming of organotropism in metastasising breast cancer cells
    Breast cancer is the most common cancer in women worldwide. It is estimated that more than 1.7 million new cases of breast cancer occurred among women worldwide in 2012. We already know that tissu...
    Breast CancerTissue stiffnessMetastasis
  • T1 | Flagship 2 Pilot and Seed
    Roger Bourne and team: Gold-standard assessment of prostate cancer MRI accuracy
    A recent health economics analysis identified doctors' lack of confidence in prostate MRI as a major inhibitor to increased choice of active surveillance for low risk prostate cancer. Furthermore,...
  • T2,T3 | Flagship 2 Pilot and Seed
    Daniel Steffens & team: Feasibility and acceptability of pre-operative exercise to improve patient outcomes after major cancer surgery: A pilot randomised controlled trial
    Promoting physical activity in the pre-operative period appears promising to improve functional capacity and facilitate post-operative recovery. This pilot study will establish the feasibility and...
    Clinical TrialsExercise
  • T1 | Flagship 3 Scholarships & Awards
    Sarah Sutherland: Novel targets for a new generation of therapeutic cancer vaccines
    DC vaccines are well tolerated and can induce an anti- tumour immune response. Current vaccine strategies use in vitro generated "DC" which are loaded with antigen, stimulated and transfused back ...
    Dendritic cellImmunotherapyUrogenital
  • T2,T3 | Flagship 3 Scholarships & Awards
    Amelia Smit: How should genomics be incorporated into Australian healthcare to improve cancer prevention and screening in the population?
    The translation of genomics has great potential to benefit cancer prevention and screening strategies in the Australian population. There is a lack of research evidence on the behavioural, psycho-...
    Genetics/genomicsSkin cancerPrevention and Early Detection
  • T2,T3 | Flagship 3 Scholarships & Awards
    Sara Wahlroos: The Effect of Exercise in combination with chemotherapy on breast cancer tumour biology, immunology and vascularisation - a non-pharmaceutical approach to current oncology treatment?
    In this study, Sara will examine the effect of exercise in mice with different breast cancer subtypes, to assess whether exercise has an additional effect in reducing tumour growth when combined w...
    Breast CancerTreatment
  • T1 | Flagship 3 Scholarships & Awards
    Ben Kong: Towards a therapeutic vaccination for glioblastoma multiforme
    The ultimate objective of Ben's research is to create an effective dendritic cell based vaccine for glioblastoma multiforme by exploiting knowledge of DC biology to find the optimum combination of...
    Dendritic cellImmunotherapy
  • T1 | Sydney Catalyst Supported
    Mark Larance: Nutrient Deprivation and the Protective Proteome for the Prevention of Disease
    Cancer is a major cause of illness and death in Australia. Key risk factors for colorectal cancer and many other cancer types are poor diet, obesity and age. In animals, short periods of nutrient ...
    Cancer metabolismColorectal cancerProteomics