Shona Ritchie

 

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Shona Ritchie is a doctoral student at the Garvan who completed a Master of Research in biomedical sciences from the University of Glasgow in 2017. She then joined A/Prof Paul Timpson's lab at the Garvan in 2018 as a research assistant. Since then, her work has focussed on molecular pathways of invasion and metastasis in pancreatic cancer. Her major projects include investigating the stromal compartment of pancreatic tumours in both murine and patient-derived models. Her ongoing work involves patient-derived xenografting (PDX) surgery to propagate patient tumour samples in mice, functional assays on patient-derived cell lines, molecular characterisation of tumour samples from genetically engineered mouse models (GEMMs) of pancreatic cancer (using mass spectrometry, 3D invasion assays, IHC, IF, western blotting, qPCR), and development of novelin vitromodels.

 

Abstract:

Investigating the long-term and pro-tumorigenic modifications of cancer-associated fibroblasts in pancreatic cancer

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